Clinical Trials

Inclusion Criteria:

• Both males and females.
• 18 years of age and above.
• Having clinical diagnosis of post-COVID syndrome.
• Having cognitive impairment based on the CNS-VS overall neurocognitive index score that is an average of the five domain scores: memory, psychomotor speed, reaction time, complex attention and cognitive flexibility.  The scale provides an age-normed standard scores with a mean of 100 and SD of 15. Scores 79 and lower are considered as “low” and as indicating “possible impairment” and scores below 70 are considered as “very low” and as indicating “impairment likely”. We will include patients who score 79 and lower.

Exclusive Criteria:

• Pregnant females.
• Presence of ferromagnetic objects in the body that are contraindicated for MRI of the head.
• Fear of enclosed spaces.
• Noise-induced hearing loss or tinnitus.
• Diagnosis of dementia before SARS-CoV-2 positive test.
• Medical conditions that can impact brain iron content such as hemochromatosis, or conditions that can impact brain function such as intractable seizure disorder, or clinically significant lab abnormalities based on the study investigator’s discretion.

Eligibility last updated 7/14/23. Questions regarding updates should be directed to the study team contact.