Point of Care Lateral Flow Assay for Coccidioidomycosis

Overview

About this study

The purpose of this study is to test the accuracy of a point-of-care lateral flow assay for coccidioidomycosis. In seropositive patients, we will take 1 drop of blood for the lateral flow test, and compare to results of the complement fixation/immunodiffusion test (standard assay) that is conducted within 2 weeks of the lateral flow assay.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Proven or probable coccidioidomycosis
Coccidioides seropositive with a detectable complement fixation titer and immunodiffusion within 3 months from study enrollment
With or without active coccidioidal symptoms at the time of blood collection.
Patient may be in receipt of antifungal treatment or observation without treatment.

Exclusion Criteria:

Immunosuppression where antibody production is anticipated to be compromised, either by underlying or acquired comorbid illness (such as but not limited to multiple myeloma, chronic lymphocytic leukemia or other hematological cancers, common variable immunodeficiency) or by medications (such as but not limited to receipt of rituximab).
Unable or unwilling to consent to study.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Janis Blair, M.D.	Closed for enrollment	Contact information: Janis Blair M.D. (480) 301-8000 Blair.Janis@mayo.edu

Mayo Clinic Location

Status

Contact

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Janis Blair, M.D.

Closed for enrollment

Contact information:

Janis Blair M.D.

(480) 301-8000

Blair.Janis@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials