Whole Food Plant-based Diet Effect on Obstructive Sleep Apnea

Overview

About this study

The purpose of this study is to assess the level of daytime sleepiness by Epworth Sleepiness Questionnaire and changes in severity of obstructive sleep apnea (OSA) in patients with OSA before and after a whole food plant-based diet intervention for a period of 8 weeks. Currently on or starting weight loss medications or new exercise regimen during the 8-week plant-based diet period.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

* Daytime sleepiness with ESS score ≥ 5.
* Patient's prior sleep study with AHI between ≥ 10 and ≤ 45 (4% scoring criterion).
* On treatment for OSA, failed or not willing to use all other OSA treatment options
* Has access to a weight scale at home or able to come into the Sleep Clinic to be weighed after the 8-week plant-based diet period.

Exclusion Criteria:

* Pregnancy or lactation.
* Current use of a vegan diet.
* BMI ≤ 22.
* Complex, central sleep apnea.
* Pre-existing significant degree of cardio-pulmonary disease-heart failure with reduced EF of 35 or lower, unstable arrythmia, severe degree of pulmonary hypertension, severe degree of obstructive or restrictive lung disease including COPD and Interstitial lung disease.
* On weight loss medications or starting new exercise regimen during the 8-week plant-based diet period.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 5/13/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Jacksonville, Fla. Mayo Clinic principal investigator Joseph Cheung, M.D.	Open for enrollment	Contact information: Clinical Studies Unit (904) 953-2255

Mayo Clinic Location

Status

Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Joseph Cheung, M.D.

Open for enrollment

Contact information:

Clinical Studies Unit

(904) 953-2255

More information

Publications

Publications are currently not available

Clinical Trials