Clinical Trials

Inclusion Criteria:

• Subjects who have planned spinal fusion surgery with Conduit/EIT cages for any indications listed below:
  • For Conduit/EIT LLIF, PLIF, ALIF, and Curved TLIF cages, degenerative disc disease (DDD) at one or two contiguous spinal levels from L2 – S1;
  • For Conduit/EIT cage, cervical disc degeneration and/or cervical spinal instability, at one or multiple contiguous levels from C2 - T1.
• Skeletally mature subjects at least 18 years of age at the time of consenting.
• Subjects had at least six (6) months of non-operative treatment prior to treatment with a lumbar intervertebral cage.
• Willing to provide voluntary written informed consent prior to participation in the registry.

Exclusion Criteria:

• Subjects who had previous fusion surgery at the index level(s).
• Subjects who have demonstrated allergy or foreign body sensitivity to the implant material.
• Pregnant subjects.
• Diagnosed with severe osteoporosis or osteopenia which may prevent adequate fixation and thus preclude the use of these or any other orthopedic implant.
• Diagnosed with severe instabilities, vertebral fractures, spinal tumors.
• Subjects who have a systemic or metabolic disease which, in the PI’s opinion, would compromise their health, safety, or ability to participate or follow-up in this registry.
• Conditions that may place excessive stress on the subject’s bone and implants, such as severe obesity. Severe obesity defined as BMI > 40 kg/m^2.
• Subjects have any acute or chronic systemic, spinal, or localized infections.
• Any medical or surgical condition precludes the potential benefit of spinal surgery, in the opinion of the PI.
• Dependency on pharmaceutical drugs, drug abuse, or alcoholism resulting in a lack of subject cooperation.
• Unable to return for a required minimum 12-month follow-up visit.
• Unable to comply, and/or in the PI’s opinion unable to comply, with the requirements of participation in the registry.

Eligibility last updated 10/21/22. Questions regarding updates should be directed to the study team contact.