Clinical Trials

Inclusion Criteria

• Longstanding history of competitive endurance athletic performance defined as > 15 years of continuous athletic training for at least 7 hours per week and ongoing engagement in competitive events.
• Between the ages of 40 - 60 years of age.

Exclusion Criteria

• A current or prior diagnosis of cardiovascular disease as defined by the presence of structural heart disease, heart failure, symptomatic coronary artery disease, more than moderate valve disease or prior valve surgery.
• Current or recent pregnancy within 1 year.
  • Positive pregnancy test (study visit 1).
• Concurrent or use within 1 year of oral contraceptives or hormone replacement therapy.
• Unable to undergo a cMRI.
  1.  
  • Please refer standard clinical contraindications for MRI.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 2/06/2024. Questions regarding updates should be directed to the study team contact.