Clinical Trials

Inclusion Criteria:

• ≥ 18 years.
• Male and female.
• Transtibial amputation expected.
• Peripheral arterial disease, Ankle Brachial Index (ABI) and Transcutaneous partial pressure of oxygen (TCP02, if performed).
• Diabetes.
• Tobacco use at any time in past or current use (pack years).
• On dialysis (hemodialysis and peritoneal).
• Prior contralateral leg amputation.
• Ability of subject to give appropriate consent or have an appropriate representative available to do so.

Exclusion Criteria:

• TcPO2 < 20 (Transcutaneous Cutaneous Partial pressure of oxygen).
• Known allergies to any of the components of the compression.
• Terminal illness or current cancer therapy with chemotherapy.
• Inability to undergo ongoing care in Rochester.
• Lack of cognitive ability to follow instructions or monitor residual limb.
• Vulnerable study population.
• Pregnancy.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 11/2/23. Questions regarding updates should be directed to the study team contact.