Clinical Trials

Inclusion Criteria:

• Females who are English speaking and are at least 18 years of age.
• Menopausal status
• Subjects presenting for 2 week post initial pessary insertion appointment or presenting for routine pessary care follow up appointment
• Planning on continuing to use a pessary for treatment for at least 3 months
• Those who are consenting and able to participate in the follow up and complete the questionnaire.

Exclusion Criteria:

• Lack of cognitive ability to consent to participate in study and to complete the questionnaires
• Planned prolapse surgery less than 3 months from enrollment
• Presence of vaginal fistulas
• Receiving immunosuppressive therapy or history of immunodeficiency
• Presence of an indwelling vascular access line or structural heart disease
• Within 6 weeks (about 1 and a half months) from any abdominal or pelvic surgery or other major surgery
• Currently using probiotics
• Currently using antibiotics or used within 4 weeks of initial vaginal swab
• Having BV or vaginitis at the time of recruitment

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 1/17/2024. Questions regarding updates should be directed to the study team contact.