Clinical Trials

Inclusion Criteria:

• Adults aged 18 and older.
• Adult male and female healthy volunteers.
• Adult male and female volunteers with diagnosed substance use disorder.
• Normal subjects must not have any confounding medical conditions.

Exclusion Criteria:

• Any ‘undefined’ metallic implants or foreign bodies inside the body.
• Implanted active devices such as cardiac defibrillators/pacemakers, deep brain stimulators, vagus nerve stimulators, intrathecal pumps, cochlear implants.
• Devices, or residual parts thereof left in the body such as cardiac pacer wires, which provide life assist, bone growth or pain management.
• Structural support devices, screws, or wires in bone that are near the spinal cord or temperature sensitive organs.
• Reconstructive metallic implants near the orbits.
• External devices, medicinal patches, piercings, jewelry, clothing or hair accessories (such as wigs, weaves and extensions) within to the radiofrequency coil that cannot be removed from the body.
• Pregnancy.
• Prisoners.
• Tattoos located within or near the radiofrequency coil.
• Permanent facial makeup (for brain scanning).
• Metallic fragment in the eye.
• Colored contact lens.
• Fever / elevated temperature.
• Suffer from claustrophobia.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 10/27/23. Questions regarding updates should be directed to the study team contact.