Clinical Trials

Inclusion Criteria: 

Cohorts 1 and 2: Non-small cell lung cancer

• Male or Female who is 18 years or older.
• Currently diagnosed with a NSCLC.
• Scheduled or will be scheduled for primary surgical resection with curative intent, with use of post-surgical drain
• The participant is cognitively able to consent to participate in the study
• The participant is healthy enough for blood draws and sample collection (at the discretion of the Investigator)

COHORTS 3 and 4: Healthy Controls/Comparators

• Male or Female who is 18 years or older.
• The participant is cognitively able to consent to participate in the study.
• The participant is healthy enough for a blood draw and sample collection (at the discretion of the Investigator).
• The patient has no history of a cancer diagnosis.
• Is scheduled to undergo a non-malignancy and non-infectious related surgical procedure, for example penetrating chest trauma, non-malignant pneumothorax, benign pleural effusion drainage, cardiac surgeries requiring chest tube placement which result in the use of surgical drain placements similar to those in cohorts 1 and 2.

Exclusion Criteria: 

COHORTS 1 and 2: Non-small cell lung cancer

• Participant does not meet all inclusion criteria.
• Subject deemed not fit to participate at the Investigator’s discretion.
• Pulmonary carcinoid tumors (well-differentiated neuroendocrine tumors).
• Neoadjuvant therapy (chemotherapy, radiation therapy, immunotherapy, or combinations).
• Participant has a history of a previous cancer diagnosis, other than: non-melanomatous localized cutaneous malignancies (e.g., SCC, BCC); non-metastatic prostate cancer; and non-metastatic well differentiated thyroid cancers within the last 5 years.  

COHORTS 3 and 4: Healthy Controls/Comparators

• Participant does not meet all inclusion criteria.
• Subject deemed not fit to participate at the Investigator’s discretion.
• Participant undergoing surgery for infectious etiology.  

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 4/4/2024. Questions regarding updates should be directed to the study team contact.