A Study of Cerebral Perfusion with tDCS in Chronic Hypoperfusion

Overview

About this study

The purpose of this study is to examine whether transcranial direct current stimulation (tDCS) will increase cerebral blood flow and translate into clinical benefit such as improving cognitive impairment.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Age 18 years of age or greater.
Vasculopathy leading to imaging evidence of hypoperfusion.
Cognitive impairment* - *Will only be sought for phase II.

Exclusion Criteria:

Pregnancy.
Contraindication to MRI or tDCS including metallic implanted objects.
Medical instability or inability to cooperate during the study as assessed by the treating physician to participate in the study.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 1/29/24. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Zafer Keser, M.D.	Open for enrollment	Contact information: Jeffrey Laivell (507) 538-8095 Laivell.Jeffrey@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Zafer Keser, M.D.

Open for enrollment

Contact information:

Jeffrey Laivell

(507) 538-8095

Laivell.Jeffrey@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials