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Delirium Phenotypes With Gut Microbiomes, EEG, Frailty, and Other Factors Among Older Adults Admitted From the Emergency Department

Overview

About this study

The purpose of this study is that subtypes of delirium exist that remain undescribed, and which could provide a foundation for subsequent delirium prevention or treatment trials that target the underlying pathophysiology manifesting as incident or prevalent delirium.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria: 

  • Older patients (age ≥ 70) admitted from the St. Mary’s ED to a medical or surgical service without a time-dependent emergency that would preclude enrollment will be eligible. 
  • Cognitive impairment, if present, will require subject assessment and proxy consent.(36)

Exclusion Criteria: 

  • Antibiotics within preceding 4-weeks, probiotics within preceding 1-week, critical illness precluding participation (intubated, unresponsive, acute ischemic stroke undergoing endovascular revascularization).

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 5/01/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Christopher Carpenter, M.D.

Open for enrollment

Contact information:

Christopher Carpenter M.D.

(507) 255-5385

Carpenter.Christopher@mayo.edu

More information

Publications

Publications are currently not available

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CLS-20574303

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