Clinical Trials

Inclusion Criteria:

• Adult patients 18 to 99 years of age
• Patients with proven rectal cancer clinically referred for staging pelvic MR and contrast-enhanced CT of the abdomen and pelvis (for evaluation of liver and peritoneal disease)
• Patients who are able and willing to sign the informed consent
• Negative pregnancy test if subject is of child-bearing age (females of child-bearing potential will be screened for pregnancy using a urine pregnancy test, which will be administered by the unit study coordinator at no cost to the patient)

Exclusion Criteria:

• Minors less than 18 years old
• Rectal cancer that is mucinous adenocarcinoma (will not enhance well on CT)[FM1] 
• Patients unable to provide written informed consent
• Pregnancy
• eGFR ≤ 60 (7, 8)
• History of prior moderate or severe contrast reaction including unresponsiveness, severe respiratory distress, convulsions, arrhythmia, cardiopulmonary distress, progressive angioedema, laryngeal edema, dyspnea, bronchospasm, symptomatic tachycardia, symptomatic bradycardia, hypotension, hypertensive crisis
• Any history of premedication prior to iodinated contrast
• Hip replacement/prosthesis.
• Patients that consent to participation but do not undergo their clinically indicated MR scanning for any reason (e.g., bad IV, infiltration, reaction, change in indication).

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 2/15/2024. Questions regarding updates should be directed to the study team contact.