Clinical Trials

Inclusion Criteria: 

• Hospitalized adults age 18 or above.
• Age 75 or above.
• Hearing impairment.
• Vision impairment.
• Initiation of 8 or new medications since start of hospitalization.
• Chronic kidney disease III or greater.
• Congestive heart failure.
• Hospitalization for 14 or more days.
• Dehydration requiring ongoing use of IV hydration.
• Electrolyte imbalance requiring ongoing correction.

Exclusion Criteria: 

• Inability to consent.
• Current pregnancy.
• Current or prior delirium in the active hospitalization.
• Use of -azole antifungals.
• Use of any benzodiazepine, benzodiazepine receptor modulator, or first generation antihistamine class medication within 72 hours prior to enrollment.
• Personal history of narcolepsy.
• Personal history of other primary sleep disorders including obstructive sleep apnea.
• Personal history of alcohol use disorder.
• Personal history of substance use disorder.
• Personal history of cirrhosis.
• Transaminitis more than 3 times the upper limit of normal.
• History of obstructive lung disease other than asthma.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 5/28/2024. Questions regarding updates should be directed to the study team contact.