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13CARBON-Based Deep Labelling of Bone Marrow Cells to Map Their Utilization of Extracellular Metabolites

Overview

About this study

The purpose of this studyis to evaluate differences in the amount of extracellular uptake of glucose and amino acids (AAs) between pre-malignant clonal plasma cells (cPCs) and polyclonal plasma
cells (pPCs).
 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • At least age 18 years or older.
  • Able to provide informed consent.For the MGUS cohort, only.
  • IMWG criteria for the diagnosis of non-IgM MGUS.

Exclusion Criteria:

  • Unable to provide consent.
  • ECOG PS >1.
  • Prior history of adverse events with conscious sedation.
  • Ongoing use of immunosuppressive medications.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 4/11/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Wilson Gonsalves, M.D.

Open for enrollment

Contact information:

Sarah Aug

(507) 538-1301

Aug.Sarah@mayo.edu

More information

Publications

Publications are currently not available

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CLS-20578812

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