Subharmonics and Subharmonic Aided Pressure Estimation for Identifying Portal Hypertension

Overview

About this study

The purpose of this study is to evaluate use of subharmonic imaging and the SHAPE technique for identifying portal hypertension (PH).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

Provide signed and dated informed consent form.
Willing to comply with all study procedures.
Adult patients (age of 18 years or older).
If a female of child-bearing potential, must have a negative pregnancy test.
Be scheduled for HVPG measurement.

Exclusion Criteria:

Females who are pregnant or nursing.
Patients with known or suspected hypersensitivity to perflutren lipid microsphere or its components, such as polyethylene glycol (PEG).

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 8/09/2024. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location	Status	Contact
Rochester, Minn. Mayo Clinic principal investigator Jaydev Dave, Ph.D.	Open for enrollment	Contact information: Beatrice Hartke Hartke.Bea@mayo.edu
Jacksonville, Fla. Mayo Clinic principal investigator Melanie Caserta, M.D.	Contact us for the latest status	Contact information: Zain Shah Shah.Zain@mayo.edu
Scottsdale/Phoenix, Ariz. Mayo Clinic principal investigator Nirvikar Dahiya, M.D.	Contact us for the latest status	Contact information: Alexander Esmeralda-Meckelburg Esmeralda-Meckelburg.alex@mayo.edu

Mayo Clinic Location

Status

Contact

Rochester, Minn.

Mayo Clinic principal investigator

Jaydev Dave, Ph.D.

Open for enrollment

Contact information:

Beatrice Hartke

Hartke.Bea@mayo.edu

Jacksonville, Fla.

Mayo Clinic principal investigator

Melanie Caserta, M.D.

Contact us for the latest status

Contact information:

Zain Shah

Shah.Zain@mayo.edu

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Nirvikar Dahiya, M.D.

Contact us for the latest status

Contact information:

Alexander Esmeralda-Meckelburg

Esmeralda-Meckelburg.alex@mayo.edu

More information

Publications

Publications are currently not available

Clinical Trials