Clinical Trials

The study will answer whether inhaled budesonide and formoterol are able to alleviate or prevent pulmonary injury when administered early in hospital course to the patients at risk for developing ARDS.

To determine if an inhaled hypertonic saline solution has any effect on lung function in patients with acute respiratory distress syndrome (ARDS).

The purpose of this study is to measure the neurodevelopmental impact incurred by children receiving usual care ECMO for PARDS.

This phase II multi-centered, randomized controlled trial of mechanical ventilation directed by esophageal pressure measurement will test the primary hypothesis that using a strategy of maintaining a minimal but positive transpulmonary pressure (PTP = airway pressure minus pleural pressure) throughout the ventilatory cycle will lead to an improvement in patient survival.

The primary purpose of this study is to measure the transpulmonary driving pressures of patients on airway pressure release ventilation (APRV) during a 1 hour period to assess how the lung responds to the mechanical breath profile of APRV with a time-controlled adaptive ventilation (TCAV) protocol.

The purpose of this study is to assess the effectiveness and safety of oral rosuvastatin for the treatment of patients who have sepsis-induced acute lung injury.

The purpose of this study is to evaluate the use of a non-invasive bedside echocardiography to assess the effect of mechanical ventilation (invasive and non-invasive) on the function of the heart.

The primary purpose of this study is to evaluate whether early treatment with therapeutic hypothermia (TH), along with neuromuscular blockade (NMB) to prevent shivering, will be beneficial to patients with Acute Respiratory Distress Syndrome (ARDS).

The purpose of this study is to deepen our understanding of the ARDS mechanism following transplantation through an analysis of cytokines, metabolomics and proteomics before ARDS occurs, and during the early phase of ARDS development.