Clinical Trials

The purpose of this study is to understand the patient perspective on which decisions should be shared during the course of treatment for carpal tunnel syndrome.

The purpose of this study is to compare the incisionless thread carpal tunnel release with the standard mini-open carpal tunnel release (standard of care) in patients with bilateral carpal tunnel syndrome.

The purpose of this study is to establish the safety and effectiveness of the ultra-minimally invasive thread carpal tunnel release technique versus the mini-open carpal tunnel release (standard of care).

The purpose of this trial is to determine if Fisetin has any effect on CTS, powered based on the results of known effective treatments of CTS. The primary hypothesis is that the Boston CTS questionnaire score will improve by 1 point from pre-treatment to 60 days post-treatment. The secondary hypothesis is that clinical improvement will be proportional to the effect in reducing blood markers of cellular senescence

The purpose of this study is to document the primary investigator’s clinical experience performing Ultrasound Guided Carpal Tunnel Release (USCTR) in the clinic procedure room setting through retrospective and prospective analysis of these now routinely collected clinical outcomes. 

The purpose of this study is to use ultrasound to detect variations in nerve, tendon and subsynovial connective tissue mobility in patients with carpal tunnel syndrome may be useful as functional biomarkers that serve as predictors for treatment response. To test this patients presenting for treatment of carpal tunnel syndrome will be monitored by ultrasound and by clinical assessment before and after non-surgical and surgical treatment.  The clinical outcomes will be alined with the initial ultrasound motion patterns.

The purpose of this study is to determine if the Patient-Specific Functional Survey (PSFS) is a valid and reliable measure to evaluate functional difficulties with carpal tunnel syndrome.

This is a pilot study designed to acquire data on the added value of hydrodissection when using a corticosteroid injection as a treatment for patients with carpal tunnel syndrome. Hydrodissection is part of a standard clinical care injection under ultrasound guidance in which the fluid is used to separate the nerve from surrounding structures.

The purpose of this study is to collect normal tissue as the control for a study looking at the role of synovial fibrosis in the development of carpal tunnel syndrome.

Investigators hypothesis is that as human age increases, the size of the carpal tunnel decreases.

The purpose of this study is to describe potential cosmetic differences in wound healing between absorbable and non-absorbable suture for wound closure of open carpal tunnel release and trigger finger pulley release, and to compare the two methods of wound closure based upon patient satisfaction, residual scar tenderness, and post-operative complications.

The purpose of this study is to develop a noninvasive way to measure pressure in the carpal tunnel using shear wave elastography (SWE), which may be useful in the diagnosis and assessment of patients with Carpal tunnel syndrome (CTS).

The purpose of this study is to access the effectiveness of over-the-counter analgesics in the management of post-operative pain after hand soft tissue surgical procedures.  These procedures would include carpal tunnel syndrome, trigger finger release, and first compartment releases in DeQuervain's syndrome.

As CTS is the most commonly diagnosed compression neuropathy of the upper extremity, assessment of severity and treatment response is important crucial to determine the clinical outcomes. Currently, physical examination and overall functional status as well as pre-op electrodiagnostic (EDX) testing are important in determining patient outcome scores and assessing the treatment response. The physical properties of MN and surrounding tissue may be good biomarkers for this evaluation.

SWE is a qualitative and quantitative method for measuring tissue stiffness. There are limited studies on using SWE for diagnosis of CTS , but other aspects of CTS, including the ...