-
Cavernous Malformation Prospective Registry
Rochester, MN
Investigators are trying to learn more about why cavernous malformations form. In addition, investigators are trying to determine which cavernous malformations might cause future symptoms and which ones may be more benign. To do this, investigators are trying to look at various lifestyle factors, medication use, and other medical problems and how they influence what happens over time
-
A Study to Assess if Using Holography/Augmented Reality and 3D-printed Models to Visualize Intracranial Diseases and Aid in Patient Education
Scottsdale/Phoenix, AZ
The purpose of this study is to assess if using holography/ Augmented Reality and 3D-printed models to visualize intracranial diseases and aid in patient education.
-
Study of Trial Readiness in Cavernous Angiomas with Symptomatic Hemorrhage (CASH)
Rochester, MN
The purpose of this study is to set up the infrastructure for future clinical trials for patients with cavernous malformations. To do this we will be assessing the quality of MRI and data collection from patients with cavernous malformations across multiple sites in the country. At Mayo, we will be looking at new MRI "sequences" in addition to the usual sequences to see if that helps determine which cavernous malformations may bleed again.
-
A Study to Assess Biomarkers of Cerebral Cavernous Angioma with Symptomatic Hemorrhage (CASH)
Rochester, MN
The purpose of this study is to develop prognostic and diagnostic blood tests for symptomatic brain hemorrhage in patients diagnosed with cavernous angiomas, a critical clinical challenge in a disease affecting more than a million Americans. We further examine whether blood biomarkers can replace or enhance the accuracy of advanced imaging in association with lesional bleeding. The project tests a novel integrational approach of biomarker development in a mechanistically defined cerebrovascular disease, with a clinically relevant context of use.