Clinical Trials

The purpose of this study is to create and evaluate a sustainable referral process from primary care to a Community Care Team (CCT) for patients with chronic conditions using an implementation science framework and qualitative methods. Ultimately, this referral process will be available to inform the CCT locally as well as state- and nation-wide.

The main purpose of this study is to evaluate the efficacy of the study drug known as LY2951742 in participants with chronic cluster headache.

The main purpose of this extended study is to evaluate the long term effectiveness of the study drug LY2951742 in patients who have chronic cluster headaches.

The purpose of this study is to identify whether there is a difference in prolactin levels between patients with chronic migraine and healthy controls. This may help to explain the sensitivity to pain those patients with chronic migraine experience and may also help to establish a target for new treatments of chronic migraine

The purpose of this study is to assess the efficacy and safety of ALD403 in the prevention of migraine headache in chronic migraineurs.

The purpose of this study is to prospectively determine what method of assessment predicts headache directionality using three standardized methods: 1) pictorial representation, 2) standardized patient survey and 3) standardized headache neurology investigator assessment.

The purpose of this study is to compare eye glass lenses that have been treated with tints, to lenses that have been treated with thin-films to reduce light sensitivity and headache in patients who have chronic migraine. It is unknown if there is an advantage to either spectacle lens treatment. Both treatments could be a novel, non-invasive addition in the treatment of chronic migraine.

The purpose of this research study is to test two medicines for migraine prevention in children and adolescents. The investigators want to see if amitriptyline and/or topiramate are better than placebo (sugar pill) in reducing headache frequency in children and adolescents ages 8 to 17 with migraines. At this time, there are no FDA approved medicines approved in the US for the prevention treatment of migraine headaches in children and adolescents.

The purpose of this study is to enroll in a registry patients who have headache disorders, collecting detailed headache characteristics, biospecimens, and brain imaging data, to allow for more research into accurate diagnosis, prognosis, and treatments.

The purpose of this study is to identify mechanisms and predictors for the persistence of post-traumatic headache and methods to treat post-traumatic headache and prevent its persistence.