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A Study to Assess Disease Activity and Safety of Subcutaneous Lutikizumab (ABT-981) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-Tumor Necrosis Factor (TNF) Therapy and Who Are Naïve to Biologic Therapy
Scottsdale/Phoenix, AZ
A Phase 2 Multicenter, Randomized, Double-Blind Placebo-Controlled Study to Evaluate the Safety and Efficacy of Lutikizumab (ABT-981) in Adult Subjects with Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti‑TNF Therapy. Amended Protocol to Include a Lutikizumab Open-Label Sub-study in Subjects Naïve to Biologic Therapy.
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A Study Investigating Long-term Treatment With Spesolimab in People With a Skin Disease Called Hidradenitis Suppurativa Who Completed a Previous Clinical Trial
Rochester, MN
The primary objective of this trial is to assess the long-term safety of spesolimab in patients with HS who have completed the 1368-0052 PoCC trial and are qualified for entry into this trial. The secondary objectives are to evaluate effectiveness at a lower dose than tested in PoCC trial.
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A Study to Evaluate the Effectiveness of Spesolimab to Treat Hidradenitis Suppurativa
Rochester, MN
The purpose of this study is to assess the effectivess and safety of Spesolimab in Hidradenitis Suppurativa (HS) patients.
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Hidradenitis Suppurativa Global Prevalence
Jacksonville, FL; Rochester, MN
The purpose of this study is to provide the first specific globally comparable prevalence data on Hidradenitis Suppurativa (HS).
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A Study to Evaluate the Safety and Effectiveness of PF-06650833, PF-06700841, and PF 06826647 in Adults With Hidradenitis Suppurativa
Evaluating the Safety and Effectiveness of PF-06650833, PF-06700841, and PF-06826647 in Adults with Moderate-to-Severe Hidradenitis Suppurativa
Scottsdale/Phoenix, AZ
The purpose of this study is to evaluate the effectiveness of PF-06650833, PF-06700841, and PF-06826647 vs placebo in participants with Hidradenitis Suppurativa (HS) as assessed by Hidradenitis Suppurativa Clinical Response (HiSCR).
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Hidradenitis Suppurativa Registry
Rochester, MN
The purpose of this study is to comprehensively characterize Hidradenitis Suppurativa (HS) from clinical and biological perspectives. Study subjects will be individuals with HS. Consented subjects will complete electronic surveys and undergo comprehensive dermatologic evaluations at designated time points. Study subjects will be asked to donate skin swabs, saliva samples, stool samples, blood samples, hair samples and/or skin specimens.
Collected biospecimens will be stored in a local tissue bank for future study. Subjective measures will be collected to characterize the effect of disease on quality of life.
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Predictors of Inflammatory Arthritis in Patients with Hidradenitis Suppurativa and Psoriasis
Rochester, MN
The purpose of this study is to identify the incidence and prevalence of inflammatory arthritis in patients with Hidradenitis Suppurativa (HS) and compare them with those in patients with psoriasis through implementing a routine screening. Identifying the incidence and prevalence of this comorbidity has the potential to increase awareness across the specialties of rheumatology and comorbid diseases.
The aims of this study are to determine the frequency, severity, and duration of symptoms of arthritis in patients with HS and compare them with those in patients with psoriasis, to determine the association between inflammatory arthritis and disease flare-ups/severity ...