Clinical Trials

The purpose of this study is to systematically examine the immunological features between IA-irAE, classic inflammatory arthritis, ICI-controls and HC.

The purpose of this study is to establish a cohort of clinical and biological samples of patients with early rheumatoid arthritis or arthritis like undifferentiated inflammatory arthritis in order to address multiple critical barriers that exist to improved outcomes for patients with RA and other chronic inflammatory arthritides, including: (1) gaps in understanding disease mechanisms; (2) the lack of highly useful diagnostic and prognostic tools; and (3) the unavailability of personalized, targeted therapies for patients with early inflammatory arthritis.
 

The purpose of this study is to compare the outcome of primary anatomic shoulder arthroplasty using the Stryker ReUnion system with implantation of either a peg or keel glenoid construction.

The purpose of this study is to identify the incidence and prevalence of inflammatory arthritis in patients with Hidradenitis Suppurativa (HS) and compare them with those in patients with psoriasis through implementing a routine screening. Identifying the incidence and prevalence of this comorbidity has the potential to increase awareness across the specialties of rheumatology and comorbid diseases.

The aims of this study are to determine the frequency, severity, and duration of symptoms of arthritis in patients with HS and compare them with those in patients with psoriasis, to determine the association between inflammatory arthritis and disease flare-ups/severity ...

Patients with active Axial Spondyloarthritis without x-ray evidence of Ankylosing Spondylitis and with signs of inflammation will be randomly assigned to receive certolizumab pegol (CZP) 200 mg every two weeks or placebo. The primary objective is to demonstrate the efficacy of CZP in these patients.

The purpose of this study is to establish a comparator cohort of patients with rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and other spondyloarthropathies. We will collect demographic information, historical information about diagnosis and past treatment, and clinical, radiographic, and laboratory data on each patient using standardized data collection forms.  We will also collect blood and synovial tissue samples from each patient.  This will provide data and material for clinical and translational research to address questions related to the fundamental differences between the spondyloarthropathies and inflammatory arthritis relating to the response of bone to chronic inflammation.  We intend to enroll sequential ...

The purpose of this study is to see if whole blood-based blood biomarker (i.e., cytokine) predicts status and severity of diseases such as asthma, Juvenile Idiopathic Arthritis (JIA), Rheumatoid Arthritis (RA), or Inflammatory Bowel Disease (IBD).