Clinical Trials

Optic neuritis

Displaying 8 studies

  • A Study to Evaluate a Color Test for Patients with Optic Nerve Diseases Rochester, MN

    The purpose of this study is to evaluate the clinical utility of a quantitative test to measure how color saturation appears in patients with diseases of the optive nerve.

  • Pediatric Optic Neuritis Prospective Outcomes Study Rochester, MN

    The primary outcome is visual acuity at 6 months. Secondary aims will be to characterize optic neuritis in a large  multicenter cohort of children and to assess the risk of development of MS at two years.

     

     

  • Evaluating Optic Nerve Disease with OCT Angiography Rochester, MN

    The purpose of this study is to determine if optical coherence tomography (OCT) angiography is able to distinguish different causes of optic neuropathy.

  • Using Critical Flicker Fusion to Distinguish Causes of Vision Loss Rochester, MN

    The goal of this study is to evaluate the efficacy of the critical flicker fusion device in distinguishing different kinds of optic neuropathy. 

  • Neuromyelitis Optica Clinical Consortium (NMOCC) Clinical Database Development for Neuromyelitis Optica Spectrum Disorders Scottsdale/Phoenix, AZ

    The primary objective is of this protocol to create a database of NMO patient information that can be queried to address specific scientific questions.  The first series of questions will focus on the clinical characteristics and course of the disease.  For example, sex ratio, ethnicity, and age of onset will be described for NMOSD as a whole and amongst the different diagnostic subcategories.  A main question of whether NMO-IgG seropositive patients differ with respect to disease activity compared with seronegative patients and exploratory multivariable analyses of the natural history will be conducted

  • Long Term Clinical Outcomes of Devic’s Disease Rochester, MN; Jacksonville, FL

    Aims, purpose, or objectives:

    1. To describe the clinical features along with treatment outcomes of a cohort of patients with a diagnosis of NMOSD after the latest revised criteria in 2015 by International Panel for Neuromyelitis Optica Diagnosis (IPND)
    2. To described the long term outcomes of a cohort of patients with a diagnosis of NMOSD
    3. To identify demographic, clinical and radiologic factors associated with long terms outcomes of NMOSD
    4. To determine if patients who are diagnosed with the revised 2015 IPND criteria, in particular those who do not satisfy previous criteria, are ultimately diagnosed with ...

  • Matched Serum and Cerebrospinal Fluid Disease Repository Rochester, MN

    The aim is to establish a repository consisting of clinical information, radiological data, serum, peripheral blood lymphocytes, plasma, cerebrospinal fluid (CSF), and tissue specimens collected prospectively from patients with CNS diseases and controls.

  • A Biorepository for the Center for Multiple Sclerosis and Autoimmune Neurology Scottsdale/Phoenix, AZ; Rochester, MN; Jacksonville, FL

    The purpose of this study is to establish a repository consisting of clinical information, radiological data, serum, peripheral blood lymphocytes, plasma, cerebrospinal fluid (CSF), urine, stool, DNA and tissue specimens collected from patients who have central nervous system (CNS)  inflammatory diseases. 

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