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A Study to Evaluate the Spectral Topogram to Predict Osteoporosis and Osteopenia
Rochester, MN
The Photon Counting Detector Computed Tomography (PCD-CT) Spectral Topogram can be resolved into multispectral components given the ability of photon counting detectors. This modality, therefore, has the ability to quantify bone mineral density and may be an alternative to dual-energy X-ray absorptiometry (DEXA) scan in the routine clinical screening of high-risk individuals for osteoporosis. PCD-CT Spectral Topogram may, therefore, be an opportunistic way to increase osteoporosis screening for individuals undergoing CT, particularly at-risk populations.
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Denosumab Stimulated Parathyroid Scan Pilot Study in Persistent or Recurrent Primary Hyperparathyroidism
Rochester, MN
The purpose of this study is to determine if denosumab prior to parathyroid scan in patients with recurrent or persistent primary hyperparathyroidism and osteoporosis or osteopenia improves localization of parathyroid adenomas.
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Bone Health in Patients with/without Adrenal Disease
Rochester, MN
The purpose of this study is to determine prevalence and incidence of osteopenia, osteoporosis, and fractures in patients with adenomas based on hormonal sub-type, and to determine the effect of abnormal steroid metabolome on bone density, bone metabolism, and fractures.