Clinical Trials

The purpose of this study is to gather clinical data to allow for comparisons in operative time, surgical technique, blood loss, level of resection, type of reconstruction, healing (based upon clinical report and imaging studies), transfusion requirements, complications, return to the operating room, and margins. There are other important data available that will also be recorded in order to draw comparisons to prior studies (Beadle, CORR 2005):  length of hospitalization, disposition at discharge, histology and grade of tumor, local recurrences, overall survival, duration of follow up, surgeon reported outcomes (MSTS 1987), chemotherapy regimen, radiation regimen, subsequent non-orthopedic oncologic surgeries.

The purpose of this study is to assess advanced imaging methods for the prostate and pelvis. Specifically, we are studying methods that allow us to acquire higher resolution images of the prostate and pelvis more quickly than our current imaging methods. These types of fast high resolution MRI acquisitions have been shown in the literature to improve cancer detection.

The purpose of this study of sulfasalazine is to see how well it works in preventing acute diarrhea in patients with cancer who are undergoing pelvic radiation therapy. Sulfasalazine may relieve diarrhea in patients with cancer who are undergoing pelvic radiation therapy.

The primary purpose of this study is to assess the feasibility of heated intra-peritoneal chemotherapy (HIPEC) with doxorubicin (DOXO) and Cisplatin (CDDP) after surgical resection of pediatric pelvic and abdominal tumors, and to assess morbidity, hospital length of stay and peri-operative mortality outcomes for pediatric patients with intraperitoneal sarcoma undergoing hyperthermic intraperitoneal chemotherapy.