Clinical Trials

Polyarteritis nodosa

Displaying 4 studies

  • A Randomized Multicenter Study for Isolated Skin Vasculitis Rochester, MN

    Multi-center sequential multiple assignment randomized trial comparing the effectiveness of three different standard of care treatment options for patients with isolated skin vasculitis.

  • Creation of a Biospecimen Repository from Patients with ANCA-associated Vasculitis Rochester, MN

    The purpose of this study is to develop a repository of serum and urine samples from patients with AAV to support future studies into the development of such biomarkers. 

  • Clinical Transcriptomics in Systemic Vasculitis (CUTIS) Rochester, MN

    Multi-center observational study to evaluate the histopathology and transcriptome of cutaneous lesions in patients with several different types of vasculitis.

  • Low Dose Naltrexone to Improve Physical Health in Patients With Vasculitis Rochester, MN

    The purpose of this clinical trial is to determine if low dose naltrexone is effective in improving health-related quality of life (HRQoL) among patients with vasculitis. Although it is a pilot study, a placebo-controlled component is used because of the prominent placebo group effect seen in studies with self-reported subjective outcomes.

    Naltrexone is an FDA approved drug (for alcoholism) that has found widespread use "off-label" to treat pain and improve quality of life at much lower doses than are used for the approved indication. There are a few scientific studies in three conditions (fibromyalgia, Crohn's disease, and multiple sclerosis) ...

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