Clinical Trials

Aims:              

1. To construct a cohort of women who underwent a stress urinary incontinence surgery from January 1, 2002 through February 28, 2012.

2. To report on the treatment outcome after surgical intervention and compare outcomes between different types of surgeries.

3. To report on the outcomes for surgical treatment of recurrent stress urinary incontinence after failed 1st surgical attempt and to compare different types of surgical interventions for the 2nd surgery.

    

This randomized, double-blind, placebo-controlled, multicenter, confirmatory study will evaluate the efficacy and safety of Cook MyoSite Incorporated Autologous Muscle Derived Cells for Urinary Sphincter Repair (AMDC-USR) compared to a placebo (vehicle) control dose in the treatment of stress urinary incontinence (SUI) in adult female patients.

The purpose of this study is to explore the prevalence of urinary incontinence (UI) among multi-ethnic refugee women in Maricopa County, Arizona, to explore the likelihood of them discussing UI symptoms with their healthcare providers, and to provide education on the topic to this population.

Does a twice weekly, 12-week Pilates pelvic floor strengthening program improve short- and long-term measures of stress urinary incontinence symptoms in women ages 45-70 years of age?

The purpose of this study is to assess the safety and effectiveness of tibial neuromodulation using the Medtronic Tibial Neuromodulation (TNM) system by demonstrating that the percentage of subjects considered a UUI responder after 6 months of tibial neuromodulation exceeds a performance goal of 40%.

GTx-024 is an orally bioavailable and tissue-selective nonsteroidal selective androgen receptor modulator (SARM) that has demonstrated androgenic and anabolic activity and is currently being evaluated as a potential treatment for stress urinary incontinence (SUI) in postmenopausal women. Urinary incontinence and pelvic floor disorders are major health problems for women, especially as they age. Pelvic floor muscle relaxation has been found to correlate with lower urinary tract symptoms including SUI. Muscles of the pelvic floor and lower urinary tract are crucial for supporting the pelvic organs and micturition; however, damage to the muscles or lack of hormonal stimulation are thought to ...

Compare baseline scores on urinary incontinence questionnaires to 2 month scores (within and between treatment groups), compare patient satisfaction scores at 2 months (between group comparison), and    compare baseline EMG to 2 month EMG scores (within and between group comparison)

The purpose of this study is to define the successful placement of the Artificial Urinary Sphincter in Men, by collecting and comparing patient subjective and objective assessment data. 

The purpose of this study is to examine correlations between stress urinary incontinence (SUI) severity and running cadence and asymmetry/performance on the 30s sit-to-stand test (SLSTS30sec) in post-partum women with SUI.

The purpose of this study is to create a Mayo Clinic AUS research database with follow-up through 4 months.  To eventually evaluate other risk factors for AUS complications, including prior treatments, comorbidities and obesity.

The purpose of this study is to assess the effectiveness and side effects of Botox solution injected through the vagina for the treatment of patients who have over active bladder (OAB), by assessing changes in an Incontinence Quality of Life Score, after three months.

Concurrent treatment of endometrial cancer and SUI may improve QOL, emotional and physical health and decrease costs for both patients and the health care system. At the time of endometrial cancer diagnosis, not only are women evaluated by a gynecologist and/or a gynecologic oncologist, but the majority will undergo surgery within weeks of their diagnosis. Thus, urinary incontinence could easily be identified, a referral made, and concurrent surgery performed. This would spare the patient two surgeries, decrease the emotional distress associated with SUI symptoms, decrease the costs associated with SUI for the patient and possibly improve overall quality of life. ...

The purpose of this study is to assess for improvement after recovering from hip surgery in the symptoms of pelvic floor disorders that existed prior to hip arthroscopy.

The purpose of this study is to assess if men and women seeking care for urological diseases have interest in support services in conjunction with standard of care.