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Effects of Background Composition, Tilt, and Rotation on Accuracy of the Subjective Visual Vertical
Rochester, MN
The primary goal of this proposal is to investigate the effects of background content on subjective visual vertical (SVV) error in patients with persistent (>3 months) vertigo, unsteadiness, or dizziness due to neuro-otologic disorders and normal individuals. The secondary goal is to correlate SVV errors with standardized measures of discomfort with space-motion stimuli, dizziness handicap, anxiety, body vigilance, neuroticism, and introversion, all of which have been identified as risk factors or core elements of persistent vestibular symptoms.
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The Development of a Dizziness Symptom Inventory (DSI)
Rochester, MN
The purpose of this investigation will be to determine the level of agreement between the "predicted" dizziness diagnosis from the DSI, compared to the "actual" diagnosis from the "gold-standard" ear (dizziness) specialist.
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Verapamil vs. Sertraline for Vestibular Migraine & Chronic Subjective Dizziness
Scottsdale/Phoenix, AZ; Rochester, MN
Chronic dizziness and recurrent vertigo are frequent complaints in primary and specialty medical care settings. Two common causes of these symptoms are vestibular migraine (VM) and chronic subjective dizziness (CSD), which may be seen in up to 25% of patients examined in tertiary neurotology centers. However, VM and CSD are relatively new diagnoses that have not yet been validated. Furthermore, recent research found that they co-exist 30% of the time with overlap in several features. From a clinical standpoint, this makes it difficult to diagnose and treat them well. From a research standpoint, it confounds subject selection for mechanistic investigations.
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Behavioral Assessment of Visual Motion Sensitivity in Individuals with Chronic Dizziness
Rochester, MN
The purpose of this study is to describe the relationship between clinical tests describing vestibular function, and behavioral tests measuring responses to dynamic visual environments.
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A Study to Determine the Feasibility of Doppler Ultrasound of Large Arterial Systems of the Brain as Vascular Involvement Markers in Presbyacusis and Presbyvestibulopathy
Jacksonville, FL
The purpose of this study is to benchmark the feasibility of carotid artery biomechanical analysis and vertebral-basilar Transcranial Doppler (TCD) as markers of vascular involvement in presbyacusis and presbyvestibulopathy.
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A Study of Factors That Predispose, Promote, and Perpetuate Post-Traumatic Dizziness
Rochester, MN
The purpose of this study is to investigate whether recent, groundbreaking discoveries about key pathophysiologic processes that drive chronic dizziness in patients without traumatic brain injury (TBI9,10) are applicable to patients with post-mTBI vestibular disability. We expect the results of this project to have practical clinical and research applications, providing novel data for two future steps: