Faculty

Donald J. Hagler, Sr., M.D.

Clinical Studies

COngenital Multicenter Trial of Pulmonic vAlve Dysfunction Studying the SAPIEN 3 interventIONal THV (COMPASSION S3) Rochester, Minn.
The purpose of this study is to demonstrate the safety and effectiveness of the Edwards Lifesciences SAPIEN 3/SAPIEN 3 Ultra RESILIA Transcatheter Heart Valve (THV) Systems in subjects with a dysfunctional right ventricular outflow tract (RVOT) conduit or previously implanted valve in the pulmonic position with a clinical indication for intervention.

Retrospective Review of Patients with Bicuspid Aortic Valve Examining the Difference in Associated Anomalies with Right and Left Cusp Fusion Versus Right and Non-Coronary Cusp Fusion Rochester, Minn.
The goal of this study is to determine whether significant differences exist in the prevalence of associated cardiac anomalies between right/left and right / non-coronary cusp fusion in bicuspid aortic valve.

Fontan extra-cardiac Conduit stenosis and stent placement (Prospective) Rochester, Minn.
The purpose of the study is to determine if extra cardiac conduit stenosis was found in Fontan patients who previously had a cardiac catheterization at Mayo Clinic and if subsequently treated with conduit stent placement in order to determine if stenting is effective in relief of clinical symptoms.
GORE® CARDIOFORM ASD Occluder Clinical Study: A Study to Evaluate Safety and Efficacy in the Treatment of Transcatheter Closure of Ostium Secundum Atrial Septal Defects (ASDs) - The Gore ASSURED Clinical Study (ASSURED) Rochester, Minn.
Evaluate the safety and efficacy of the GORE® CARDIOFORM ASD Occluder in the percutaneous closure of ostium secundum atrial septal defects (ASDs)
Pediatric International Bicuspid Aortic Valve Consortium Rochester, Minn.
The purpose of this registry is to collect data and imagery, to study children and adults under the age of 21 who were born with bicuspid aortic valve disease. Some types of bicuspid aortic valves might be more likely associated with greater disease severity such as the degree of stenosis or valve leakage and possible enlargement of the aorta.