Clifford R. Jack, Jr., M.D.

Closed for Enrollment

• Dominantly Inherited Alzheimer Network - Therapeutic Treatment Unit (DIAN TU) Rochester, Minn. This is a subaward with Washington University in St. Louis (Wash U) as the prime site. This study is designed to assess the efficacy of drug treatment to pre-AD subject. Dr. Jack's ADIR lab will have no patient contact and will only receive de-identified data from Wash U. ADIR will assess the images for MRI protocol compliance and quality. Neuroradiologists in the lab will provide safety assessments and provide inclusion/exclusion recommendations. Mayo Clinic in Rochester will also be a safety MRI site for local participants who are enrolled at other performance sites. Research participants are required to have MR safety scans to ensure safety for continued participation at their respective enrollment site. These safety scans can be done at a clinic/hospital close to their home for patient convenience.