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  • Fatty Infiltration Of The Opponens Pollicis Muscle And Thumb Carpometacarpal Arthritis ( ) Rochester, Minn.

    The purpose of this study is to identify pro-inflammatory factors (cytokines or SASP) in cells obtained from OP FI and OP muscle biopsies taken from patients undergoing CMC arthroplasty. To assess the responsiveness of cells obtained from OP FI and OP muscle biopsies to pro-inflammatory cytokines commonly found in synovial fluid or circulating blood of patients with OA.
  • Ultrasound Analysis Of Hand Function ( ) Rochester, Minn.

    The purpose of this study is to develop novel ultrasonographic methods for the evaluation and diagnosis of hand pathology.

Closed for Enrollment

  • DUCATS Trial: Dynamic Ultrasound to Enhance Understanding of Carpal Tunnel Syndrome (DUCATS) Rochester, Minn.

    The purpose of this study is to use ultrasound to detect variations in nerve, tendon and subsynovial connective tissue mobility in patients with carpal tunnel syndrome may be useful as functional biomarkers that serve as predictors for treatment response. To test this patients presenting for treatment of carpal tunnel syndrome will be monitored by ultrasound and by clinical assessment before and after non-surgical and surgical treatment.  The clinical outcomes will be alined with the initial ultrasound motion patterns.
  • Harvest Of Human Adipose (Fat), Bone Marrow and Tendon Cells Rochester, Minn.

    The goal of this study is to collect tissue for a research project in which tendinopathy is induced in immunocompromised rats.
  • Hydrodissection as a Treatment for Carpal Tunnel Syndrome Rochester, Minn.

    This is a pilot study designed to acquire data on the added value of hydrodissection when using a corticosteroid injection as a treatment for patients with carpal tunnel syndrome. Hydrodissection is part of a standard clinical care injection under ultrasound guidance in which the fluid is used to separate the nerve from surrounding structures.
  • Phase 2 Clinical Trial of FIsetin to Treat CArpal Tunnel Syndrome (FITCATS) (FITCATS) Rochester, Minn.

    The purpose of this trial is to determine if Fisetin has any effect on CTS, powered based on the results of known effective treatments of CTS. The primary hypothesis is that the Boston CTS questionnaire score will improve by 1 point from pre-treatment to 60 days post-treatment. The secondary hypothesis is that clinical improvement will be proportional to the effect in reducing blood markers of cellular senescence
  • Study of Normal Subsynovial Connective Tissue and Carpal Tunnel Syndrome Rochester, Minn.

    The purpose of this study is to collect normal tissue as the control for a study looking at the role of synovial fibrosis in the development of carpal tunnel syndrome.
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