Kevin C. Halling, M.D., Ph.D.

Open

• Development of a droplet digital PCR (ddPCR) assay for the detection of mutant circulating tumor (ct)DNA in patients with uveal melanoma Rochester, Minn.

  The purpose of this study is to design, develop and assess the performance characteristics of a ddPCR assay for the detection of mutations associated with uveal melanoma. The performance characteristics of the ddPCR assay for the detection of ctDNA mutation in uveal melanoma patients will be assessed by comparing the mutation results obtained for the ddPCR assay on blood to those obtained on paired paraffin embedded tumors.