Kelly T. Dunagan, R.N.

Closed for Enrollment

• Dual-Hormone Control of Post-absorptive and Post-prandial Glucose in Type 1 Diabetes Rochester, Minn.

  The primary goal of this study protocol is to determine the candidate ratio of pramlintide and insulin co-infusion in individuals with type 1 diabetes (T1DM) to enable stable glucose control during the overnight post-absorptive and in the postprandial periods.

• Effects of Nocturnal Rise in Cortisol on Endogenous Glucose Production in Type 2 Diabetes Rochester, Minn.

  The purpose of this study is to assess the effects of a nighttime rise in cortisol on the body's glucose production in type 2 diabetes.

• Measuring Glucagon Kinetics in Humans: A Pilot Study Rochester, Minn.

  Our goal in this pilot study is to test and develop a novel method that will accurately measure, in vivo, glucagon kinetics in healthy humans and generate preliminary data in type 1 diabetes (T1DM) subjects under overnight fasted conditions.

• Pilot Study to Determine Effect of Exercise on Insulin Action in Type 1 Diabetes Rochester, Minn.

  The purpose of this study is to gather preliminary data to better understand acute effects of exercise on glucose metabolism. We will address if subjects with Type 1 Diabetes (T1D) are more insulin sensitive during and following a short bout of exercise compared to healthy controls. We will also determine insulin dependent and insulin independent effects on exercise in people with and without type 1 diabetes.

• To Determine the Nocturnal Pattern in Rates of EGP in Type 2 Diabetes Rochester, Minn.

  The purpose of this study is to understand nighttime glucose regulation in humans and find if the pattern is different in people with Type 2 diabetes