Filter Results

Clinical Studies

Open

  • Achieving Equity through Socioculturally-informed, Digitally-Enabled Cancer Pain Management (ASCENT) - Main Trial Rochester, Minn., Scottsdale/Phoenix, Ariz.

    The purpose of this study is to test a validated collaborative care model-based intervention aimed at improving pain control among rural dwelling and Hispanic cancer survivors by promoting multimodal pain care (MMPC)  to reduce inappropriate opioid use and by  addressing social determinants of health (SDOH) that impede patients’ access to appropriate care.
  • Mayo Clinic Community Research Registry Scottsdale/Phoenix, Ariz., Jacksonville, Fla., Rochester, Minn.

    The primary goal of this study is to establish a database of underrepresented populations who consented to be contacted for biomedical research including clinical trials and bio-specimen research. The database will serve as sampling frames for selecting healthy individuals who initially meet specific study eligibility criteria.
  • Project Hope: Achieving Home Discharge for Institutionally-bound Patients with PROMs, AI and the EHR Rochester, Minn.

    The purpose of this study is to develop a novel mCAT to assess subdomains of functional coginition relevant to safe home discharge for patients with Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD). The goal of Project HoPe is to avoid unnecessary discharges from hospitals to skilled nursing (SNF)  or other post-acute care (PAC) facilities for all patients, but particularly those with AD/ADRD. 
  • Project HoPe: Achieving Home Discharge for Institutionally-bound Patients with PROMs, AI, and the EHR – Calibration Study (HoPe Calibration) Rochester, Minn.

    The purpose if this study is to develop a novel MCAT (multidimensional computerized adaptive test) to assess subdomains of functional cognition relevant to safe home discharge to determine a patient’s need for clinician assessment and cognitive rehabilitation services. This will be done through administering candidate PRO items (questionnaire) to hospitalized patients. 

Closed for Enrollment

  • Computerized Adaptive Testing to Direct Delivery of Hospital-Based Rehabilitation Rochester, Minn.

    The purpose of this study is to create a computerized multidimensional assessment that can quickly assign hospitalized patients to ability-matched rehabilitation care plans, in three essential areas; Mobility, Daily Activity, and Applied Cognition (ability to think/problem solve).
  • Describing the Determinants and Effects of Variation in the Adoption and Use of the NOHARM Pain Management Intervention Among Diverse Surgical Practices Rochester, Minn., Jacksonville, Fla.

    The purpose of this study is an effort to enrich the ongoing NOHARM pragmatic trial. NOHARM AIM 3 will use a mixed methods analysis of patient and care team factors that affect the adoption, implementation and use of the NOHARM intervention using Epic reports, conduct chart reviews and patient interviews, as well as obtain feedback via suveys.
  • Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial  (E2C2) Rochester, Minn.

    The Enhanced, EHR-facilitated Cancer Symptom Control (E2C2) Pragmatic Clinical Trial will determine whether systematically assessing patient reported outcomes for sleep disturbance, pain, anxiety, depression, and fatigue among patients with solid and liquid malignancies and using these data to increase the frequency of guideline-concordant care by: 1) reporting these data to their clinical teams, 2) providing patients with needs-matched symptom self-management education, and 3) suggesting evidence-based symptom management strategies to their care teams improves patients' quality of life, symptoms, and adherence to cancer treatment, while reducing their unplanned use of healthcare resources.

     
  • MC1193, Collaborative Care to Preserve Performance in Cancer (COPE) Rochester, Minn.

    This randomized clinical trial studies collaborative targeted case management in improving functional status in patients with stage III-IV cancer. Collaborative targeted case management may improve functional status and preserve performance in patients with advanced cancer
  • Pilot Test of a Pain Management Intervention Preparatory to a Future Pragmatic Trial (ASCENT) (ASCENT) Scottsdale/Phoenix, Ariz., Rochester, Minn. This clinical trial tests how well a pain management intervention preparatory to a future pragmatic trial works in rural dwelling and Hispanic cancer survivors. Cancer pain is a key case study in health disparities in the United States. Cancer pain is prevalent, under treated, and remains a major cause of suffering, impairment, and disability for millions of Americans. Individual pain interventions and care models show promise for cancer pain in controlled settings. Hispanic and rural-dwelling cancer survivors stand to benefit the most from electronic health record innovations, as each of these health disparities populations experience profound disparities in pain outcomes, including marked under- and over-prescribing of opioids. Additionally, Hispanics not only comprise a steadily growing proportion of cancer survivors, but are also increasingly immigrating to rural communities, potentially placing them at "double risk" for poor outcomes. This trial will allow for the refinement of pain management intervention components that could help the management of cancer-related pain in rural dwelling and Hispanic cancer survivors.
.