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Clinical Studies

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  • Advanced Care Planning in Dementia Jacksonville, Fla.

    The goal of this study is to gain a better understanding of the status of advanced care planning among caregivers of patients with dementia and examine how this differs by race and disease stage.

Closed for Enrollment

  • A Cross-sectional, Multinational, Noninterventional Study to Evaluate the Psychometric Comparability of Culturally Adapted Versions of the Global Preclinical Alzheimer’s Cognitive Composite (G-PACC) Jacksonville, Fla.

    The main goal of this study is to evaluate whether a certain set of memory and thinking tests that are in English also work in other languages after they are translated. The measures will test your memory, thinking, problem solving, and everyday function abilities.
  • ARMADA: Advancing Reliable Measurement in Alzheimer's Disease and Cognitive Aging (ARMADA) Jacksonville, Fla.

    This study seeks to validate and further develop the NIH Toolbox for Assessment of Neurological and Behavioral Function® (NIHTB) for use in studies of cognitive aging beginning with normal cognition through progression into amnestic Mild Cognitive Impairment (aMCI) and into dementia of the Alzheimer’s Type, early stage (DAT).
  • Mayo Test Development Through Rapid Iteration, Validation and Expansion (Mayo Test Drive) (MTD) Rochester, Minn., Jacksonville, Fla.

    The overall goal of this research is to develop and validate online tests of memory and thinking. We will determine the feasibility, reliability, and validity of computerized tests that can be completed remotely, that is, without requiring a clinical or research visit. Mayo Test Drive is a web-based platform that allows for self-administration of cognitive measures on a smartphone or alternative device (e.g., PC, tablet). This flexible approach is necessary to increase access to cognitive assessment and reduce healthcare disparities. Our team has developed a novel word list learning test optimized for remote assessment via smartphone that was designed to be sensitive to subtle memory changes. We also include an open-source measure of processing speed. This study will help establish the psychometric properties and normative standards of these tests and determine their ability to detect cognitive changes with age and with different medical conditions.
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