Elie F. Berbari, M.D., M.B.A.

Closed for Enrollment

• A Phase 2b, Randomized, Double-blind, Placebo-controlled Study To Evaluate The Safety And Efficacy Of Staphylococcus Aureus 4 Antigen Vaccine (sa4ag) In Adults Undergoing Elective Open Posterior Spinal Fusion Procedures With Multilevel Instrumentation (STRIVE) Rochester, Minn.

  The purposes of the clinical trial are to determine whether the SA4Ag vaccine can prevent postoperative Staphylococcus aureus infections in patients who are undergoing elective spinal fusion surgery, and to evaluate the safety of SA4Ag in patients who are undergoing elective spinal surgery.

• Assessing the Utility of Disc Space Aspirate Cell Count and Differential in the Diagnosis of Native Vertebral Osteomyelitis Rochester, Minn.

  The purpose of this study is to validate the utility of disc space aspirate cell count and differential in the diagnosis of NVO in a large patient cohort, and propose an updated algorithm for the workup of Native Vertebral Osteomyelitis (NVO) based on disc space aspirate cell count and differential

   

• Outcome of Patients with Prosthetic Joint Infection, A Prospective Two Site Cohort Study: The Mayo Clinic, Rochester MN and Endo Klinik, Hamburg Germany Rochester, Minn.

  The purpose of this study is to assess the outcome of prosthetic joint infection (PJI) treated with various therapeutic regimens using a prospective cohort study.

• Rapid Throughput Screening for Human COVID-19 Infection: A ECG study (RACE) Rochester, Minn., Jacksonville, Fla., Scottsdale/Phoenix, Ariz.

  The purpose of this study is to determine the safety and feasibility of the POC AI-ECG’s ability to detect active SARS-Cov-2 infection in humans, and to determine specificity, sensitivity, and diagnostic accuracy of POC AI-ECG’s detection of human with COVID-19 when compared to a PCR test.

   

• Redefining Outcomes in Patients with Prosthetic Joint Infections: A Delphi Method Based Approach to Standardization Rochester, Minn.

  The aim of this study is to create a standard set of outcome parameters which can be adopted nationwide from which to gauge outcomes in Prosthetic Joint Infections (PJI).