Aida N. Lteif, M.D.

Closed for Enrollment

• Adrenocortical Carcinoma in Children: A Clinico-pathologic Analysis of 41 patients at Mayo Clinic from 1950-2015 Rochester, Minn.

  Adrenocortical carcinoma (ACC) is an aggressive, rare childhood cancer. Limited evidence exists on a definite histopathological criterion to differentiate ACC from adrenocortical adenomas. Early diagnosis and management is the key. Surgery is the mainstay of treatment. Even after complete resection, a high risk of recurrence of ACC remains. Despite multi-modality treatment strategies, ACC is associated with poor survival. Due to the rarity of pediatric ACC, limited evidence exists on morbidity and mortality of these patients as well as prognostic factors for survival. The aim of this study is to document morbidity and mortality of children with adrenocortical carcinoma (ACC) and identify prognostic factors for survival.

• Association Between Adverse Childhood Experiences and Glycemic Control and Depression in Children, Adolescents and Young Adults with Type 1 Diabetes Rochester, Minn.

  The purpose of this study is to see if there is a connection between bad experiences in the patient's childhood, either by the patient or the parent, and poor blood sugar control, obesity, poor blood lipid levels, and depression in patients with type 1 diabetes.

• Can Molecular Testing Improve Newborn Screening Performance and Outcomes for Congenital Adrenal Hyperplasia? Rochester, Minn.

  The objective of this study is to evaluate the role of molecular testing to improve newborn screening (NBS) for congenital adrenal Hyperplasia (CAH).

• Novel Predictors of Hypothalamic Obesity Rochester, Minn.

  The purpose of this study is to learn more about the changes in levels of Spexin, leptin and other biomarkers such as adiponectin and resting energy expenditure before and after hypothalamic surgery.