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Clinical Studies
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A Phase III, Multi-centre, Multi-national Randomised Control Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma (MelMarT)
Scottsdale/Phoenix, Ariz.
The purpose of this study is to determine differences in the rate of local recurrence and melanoma specific survival. A reduction in margins is expected to improve quality of life to back up evidence that less radical margins of excision may be just as safe.
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GENetic Risk Estimation of Breast Cancer Prior to Decisions on Preventive Therapy Uptake, Risk Reducing Surgery or Intensive Imaging Surveillance: A Study to Determine if a Polygenic Risk Score Influences the Decision Making Options Amongst High Risk Women (GENRE 2) (GENRE2)
Rochester, Minn.,
Jacksonville, Fla.,
Scottsdale/Phoenix, Ariz.
The primary aim of this study is to determine if the addition of an individual polygenic risk score (PRS) in addition to the Breast Cancer Risk Assessment Tool (BCRAT) or Tyrer-Cuzick (IBIS) score will aid women at risk of breast cancer in making a decision to take (or not take) medications to prevent breast cancer.
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Living Breast Organoid Biobank for Translational Research
Jacksonville, Fla.,
Rochester, Minn.
Researchers at Mayo Clinic are developing a Biobank of adult stem cell-rich breast organoids, a new research resource to facilitate normal and cancer stem cell research. Subjects in the Biobank will provide samples of excess breast tissue, complete a health questionnaire, and allow access to medical records now and in the future. The Biobank serves as a library for researchers; instead of having to look for volunteers for each new project, researchers can use samples from the Biobank as well as share information already collected.
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MC220301 Targeted Prevention of Post-Partum-Related Breast Cancer
Rochester, Minn.,
Scottsdale/Phoenix, Ariz.
The purpose of this study is to test whether a short course of aspirin can change the markers of inflammation in patients who have a benign finding within five years of their last pregnancy, and possibly reduce their risk of future breast cancer.
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Pre-analytical Factors Affecting ctDNA Analysis in Early and Locally-advanced Breast Cancer
Scottsdale/Phoenix, Ariz.
The purpose of this study is to evaluate the impact of blood collection tube type and processing methods on ctDNA, evaluate the impact of long-term storage of plasma and extracted DNA, and evaluate ctDNA levels at baseline and during treatment for patients with Stage I-III breast cancer.
Contact Us for the Latest Status
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MC220301 Targeted Prevention of Post-Partum-Related Breast Cancer
Jacksonville, Fla.
The purpose of this study is to test whether a short course of aspirin can change the markers of inflammation in patients who have a benign finding within five years of their last pregnancy, and possibly reduce their risk of future breast cancer.
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Sentinel Lymph Node Working Group
Scottsdale/Phoenix, Ariz.
The purpose of this study is to establish and analyze a large database on the outcomes of patients undergoing selective SLND, we hope to correlate a pattern of recurrence with selected patient characteristics. These results have the potential of giving physicians the ability to predict outcomes for future cancer patients and provide them a more effective course of treatment.
Closed for Enrollment
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Analysis of Circulating Tumor DNA in Breast Cancer: Can We Predict Pathological Complete Response following Neoadjuvant Treatment?
Scottsdale/Phoenix, Ariz.
This project will investigate whether ctDNA analysis in newly diagnosed stage I, II, III breast cancer patients treated with neoadjuvant systemic therapy can predict pathological Complete Response (pCR).
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Breast Cancer Conditionally Reprogrammed Cell (CRC) Study
Scottsdale/Phoenix, Ariz.
The purpose of this study is to collect blood and tissue samples for research of cancer.
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Evaluation of Surgical Outcomes and Quality of Life after Breast Reconstruction
Scottsdale/Phoenix, Ariz.
The purpose of this study is to investigate the surgical outcomes that patients have after breast reconstruction, and to assess how reconstruction has affected their quality of life.
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Living Breast Organoid Biobank for Translational Research
Scottsdale/Phoenix, Ariz.
Researchers at Mayo Clinic are developing a Biobank of adult stem cell-rich breast organoids, a new research resource to facilitate normal and cancer stem cell research. Subjects in the Biobank will provide samples of excess breast tissue, complete a health questionnaire, and allow access to medical records now and in the future. The Biobank serves as a library for researchers; instead of having to look for volunteers for each new project, researchers can use samples from the Biobank as well as share information already collected.
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Octreotide Scan versus PET Scan in Diagnosis and Follow-up in Patients with Carcinoid and Neuroendocrine Tumors
Scottsdale/Phoenix, Ariz.
The purpose of this study is to determine if octreotide scans are more sensitive than PET scans for diagnosing carcinoid or neuroendocrine tumors.
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