John G. Park, M.D.

Closed for Enrollment

• Can a Sleep Health ‘App’ Help First-Time Users of Positive Airway Pressure Therapy for Sleep Apnea Scottsdale/Phoenix, Ariz., Rochester, Minn.

  The purpose of this study is to test the usefullness and initial effectiveness of an mHealth smartphone app to increase use of positive airway pressure (PAP) therapy in obstructive sleep apnea (OSA) patients treated at the Mayo Clinic Arizona Center for Sleep Medicine.

• Neuromodulation Therapy Device for the Treatment of Sleep Apnea Rochester, Minn.

  The purpose of this study is to test a new device for the treatment of obstructive sleep apnea that delivers an auditory tone to affect neuromodulation while minimizing sleep disturbance.

• Treatment of Septic Shock by Inhibiting Autodigestion and Preserving Gut Integrity with Enteric LB1148 (SSAIL Trial) (SSAIL) Rochester, Minn.

  Septic shock is a potentially life-threatening condition that can result in multi-organ dysfunction syndrome (MODS) and mortality. LB1148 was formulated to preserve gut integrity during physiological shock and help decrease the subsequent autodigestion leading to MODS and mortality. The purpose of this study in septic shock patients is to determine if enteral administration of LB1148 will increase the number of days alive without cardiovascular, pulmonary or renal replacement therapy through Day 28.