Todd J. Schwedt, M.D.

The purpose of this study is to identify mechanisms and predictors for the persistence of post-traumatic headache and methods to treat post-traumatic headache and prevent its persistence.

The purpose of this study is to identify mechanisms and predictors for the persistence of post-traumatic headache and methods to treat post-traumatic headache and prevent its persistence. This study will address individual projects not covered by IRB 19-003200 and is done at the request of the DOD.

The purpose of this study is to determine the effectiveness of intranasal zavegepant 10 mg for the acute treatment of migraine attacks when used by those also taking CGRP targeted migraine preventive medications.

The purpose of this study is to develop an MRI based model to accurately identify persistent posttraumatic headache related to mild traumatic brain injury, as different from chronic migraine.

The purpose of this study is to enroll in a registry patients who have headache disorders, collecting detailed headache characteristics, biospecimens, and brain imaging data, to allow for more research into accurate diagnosis, prognosis, and treatments.

The specific aim of this project is to systematically and prospectively collect and collate data derived from the clinical care of concussion patients seen at Mayo Clinic Arizona.

There are two commonly used treatment strategies for treating patients who have chronic migraine with medication overuse. This study will compare the outcomes amongst patients randomized to one of the two treatment strategies.

The purpose of this study is to build on previous work, replicating the experimental protocol for subconcussive intervention with soccer headers, while adding EEG measurements and using modern machine learning (ML) techniques to create a highly accurate diagnostic algorithm.

The purpose of this study is to test the accuracy of a previously developed algorithm for predicting patient outcomes to migraine preventive treatments. Also, to optimize the performance of a previously developed algorithm for predicting patient outcomes to migraine preventive treatments.

The purpose of this study is to identify changes in brain function and structure that correlate with response to erenumab, and to develop models using imaging data to predict which patients will respond to erenumab.

The purpose of this study is to prospectively determine what method of assessment predicts headache directionality using three standardized methods: 1) pictorial representation, 2) standardized patient survey and 3) standardized headache neurology investigator assessment.

The purpose of this study is to predict migraine headache onset from changes in speech in people who have a history of migraines.