Faculty

Michael J. Marino, M.D.

Clinical Studies

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Medical Intervention Effect on Sinonasal Inflammation in Patients with Chronic Sinusitis with Nasal Polyps and Positive Sinus Culture Jacksonville, Fla., Scottsdale/Phoenix, Ariz.
The purpose of this study is to compare change in SNOT-22 score in patients who received medication therapy such as oral antibiotics, topical antibiotics, oral corticosteroids, topical corticosteroids, leukotriene receptor antagonist, and interleukin 5 receptor antagonist following endoscopic sinus surgery versus control in patient with chronic sinusitis with nasal polyps and a positive culture.

Closed for Enrollment

Outcomes of Positive Pressure Therapy for Obstructive Sleep Apnea Following Endoscopic Sinus Surgery (CPAP study) Rochester, Minn., Scottsdale/Phoenix, Ariz.
The purpose of this study is to:
1. Evaluate if there are detrimental effects of restarting CPAP therapy on POD #0-1 in patients undergoing ESS compared to normal controls undergoing ESS without OSA.
2. Determine if there a difference in perception of pain and post-operative analgesia requirement in OSA patients restarting CPAP on POD #0-1 compared to non-OSA patients.
3. Determine if there are predictive factors for OSA patients undergoing ESS who require an overnight hospitalization after surgery.
4. Validate the nocturnal Rhinoconjuctivitis Quality of Life (nRQLQ) questionnaire in the CRS population.

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