Stephanie F. Polites, M.D., M.P.H.

Open

• AOST2031, A Phase 3 Randomized Controlled Trial Comparing Open vs Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma Rochester, Minn.

  The purpose of this study is to determine if open surgical resection is superior to thoracoscopic resection for thoracic event-free survival (tEFS) in patients with resectable oligometastatic pulmonary osteosarcoma.

  Furthermore, to determine if open surgical resection is superior to thoracoscopy for event free survival (EFS), for overall survival (OS), and if thoracoscopy is superior to open surgical resection for postoperative pain interference in patients with resectable oligometastatic pulmonary osteosarcoma.

• Ruling Out Clinically Significant Injury in Children at Point-of-care Using a Biomarker Panel and Digital Microfluidic Platform Rochester, Minn.

  The purpose of this study is to create a point of care (POC) biomarker panel for pediatric trauma patients using a novel platform that will be a highly sensitive, low cost, noninvasive approach to ruling out clinically significant injuries in children presenting for trauma evaluation.