Faculty

Stephanie F. Polites, M.D., M.P.H.

Clinical Studies

AOST2031, A Phase 3 Randomized Controlled Trial Comparing Open vs Thoracoscopic Management of Pulmonary Metastases in Patients With Osteosarcoma Rochester, Minn.
The purpose of this study is to determine if open surgical resection is superior to thoracoscopic resection for thoracic event-free survival (tEFS) in patients with resectable oligometastatic pulmonary osteosarcoma.

Furthermore, to determine if open surgical resection is superior to thoracoscopy for event free survival (EFS), for overall survival (OS), and if thoracoscopy is superior to open surgical resection for postoperative pain interference in patients with resectable oligometastatic pulmonary osteosarcoma.
Pediatric Extracranial Solid Tumor Biorepository (PSTB) Rochester, Minn.
The purpose of this study is to create a biospecimen repository for both fresh frozen tissue from core needle biopsies and tumor resections as well as serial plasma collection.
Ruling Out Clinically Significant Injury in Children at Point-of-care Using a Biomarker Panel and Digital Microfluidic Platform Rochester, Minn.
The purpose of this study is to create a point of care (POC) biomarker panel for pediatric trauma patients using a novel platform that will be a highly sensitive, low cost, noninvasive approach to ruling out clinically significant injuries in children presenting for trauma evaluation.

MC250701: Pafolacianine for Localization of Pediatric Extracranial Solid Tumors Rochester, Minn.
The purpose of this study is to determine the utility of NIR fluorescent imaging using the molecular imaging agent CYTALUX for identifying lesions in children and adolescent patients with primary or metastatic solid tumors.

Digital Biomarker and Omics-Based Assessment of Surgical Resiliency in Children Undergoing Solid Tumor Resection: A Pilot Feasibility Study (Surgical Resiliency in Children) Rochester, Minn.
The purpose of this study is to demonstrate 1) feasibility of digital biomarker assessment using wearable in children with solid tumors who undergo surgery and 2) alterations in circulating proteins and metabolites indicative of a stressed state will persist postoperatively and correlate with clinical signs of recovery.