Mohamad Bydon, M.D.

The purpose of the present study is to investigate the safety and efficacy of a single intrathecal injection of autologous, culture expanded AD-MSCs specifically in subjects with severe traumatic SCI when compared to patients undergoing physical therapy.

The objectives of this study are to assess the feasibility of using Fitbits as a healthcare surveillance tool in the elderly population, to compare how Fitbit’s compare with PROMIS questionaries in terms of capturing postoperative outcomes, and to determine the benefits and limitations of Fitbits as a healthcare tool for spine surgeons.

The objectives of this study are to determine the effect of Human Umbilical Cord MSCs Derived Exosome / Extracellular Vesicle (uEV) on adult neural stem cells (NSCs) in-vito, and to assess the functional benefit of human uEV treatment on rats with spinal cord injury.

The purpose of this study is to:

1. To use natural language processing techniques applied to Twitter posts during a 1 month pre and 3 month postoperative surveillance of patients undergoing spine surgery in an effort to identify risk of 30-day postoperative complications, as well as long-term improvement in symptoms.

2. To use signal processing analytics applied to mobility data gathered from smartphone accelerometers (e.g. iPhone health app) during a 1 month pre and 3 month postoperative surveillance of patients undergoing spine surgery in an effort to identify risk of 30-day postoperative complications, as well as long-term improvement in symptoms.

3. To correlate #1 and #2 with A. patient baseline disease severity with regard to functional status according to patient reported outcome surveys (e.g. Owestry Disability Index and PROMIS10), B. Postoperative changes with regard to the metrics defined in section A, and C. traditional postoperative quality metrics (e.g. 30-day readmission, reoperation, length of stay)

The primary purpose of this study is to compare postsurgical opioid consumption through 72 hours postsurgery in patients receiving local infiltration analgesia (LIA) with EXPAREL and bupivacaine HCl (EXPAREL group) with that of patients receiving standard of care (SOC) (control group) in adult subjects undergoing posterior lumbar spine surgeries where both groups are receiving a multimodal pain regimen.

The purpose of this study is to compare outcomes of decompression alone and decompression and fusion for patients with a recurrent disc herniation.

The purpose of this study is to compare the stimulation threshold and accuracy of pedicle versus cortical trajectory screws

The purpose of this study is to determine if there are any changes in handwriting of patients with cervical spondylotic myelopathy, and assess the value of handwriting changes as an early predictor in the disease.

The purpose of this study is to identify molecular mechanisms that control the rate of disc-dehydration, the effect of degeneration on surrounding bone and ligaments, and identify agents that can be used to alter the course of the disease.

The purpose of this study is to use a patient monitoring application that monitors physiological data, psychosocial data, and responses to survey questions collected during a one month pre and three and six month postoperative observation period.

The purpose of this study is to conduct a randomized control trial comparing patient outcomes and satisfaction with or without expert panel review before making a final decision about surgery for grade I degenerative lumbar spondylolisthesis.

The purpose of this study is to evaluate the safety and effectiveness of the Spineology Interbody Fusion System (SIFS) mesh device when implanted in the spinal vertebrae disc space during a lumbar fusion procedure.

The purpose of this minimal risk evaluation is to collect data that reports on the clinical outcomes of patients treated with the Rampart Duo device in an instrumented lateral lumbar interbody fusion procedure performed at one or two contiguous levels. Data obtained will be used to support publication and podium opportunities.