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  • Describing Discomforts Among Intensive Care Unit Patients Rochester, Minn.

    The primary purpose of this study is to assess and describe the contributing sources of discomfort(s) experienced by ICU patients utilizing the Discomforts Perceived by ICU Patients instrument, a modified version of the Inconforts des Patients de REAnimation questionnaire (IPREA).

Closed for Enrollment

  • Comprehensive Symptom Assessment of ICU Patients Receiving Noninvasive Ventilation Rochester, Minn.

    The primary objective of this study is to identify the presence, intensity and distress of symptoms in patients receiving noninvasive ventilation in the ICU using a modified version the Edmonton Symptom Assessment Scale (ESAS).

    The secondary objective is to describe the most frequent and most distressing symptoms experienced by patients receiving NIV in the ICU.
  • Decreasing Delirium Through Music in Critically Ill Older Adults (DDM) Rochester, Minn.

    The purpose of this study is to evaluate the effectiveness of a seven-day slow-tempo music intervention on the primary outcome of delirium/coma free days among mechanically ventilated, critically ill older adults.

    Critically ill older adults admitted to the intensive care unit (ICU) are at a higher risk to develop delirium, which predisposes them to longer lengths of ICU and hospital stay, increased in-patient mortality, and higher risk of new acquired cognitive impairment and dementia. Music listening is a non-pharmacological intervention that holds potential to decrease ICU delirium.

     
  • Efficacy of Self-management of Sedative Therapy by Ventilated ICU Patients Rochester, Minn.

    The purpose of this randomized clinical trial is to test the efficacy of dexmedetomidine for the self-management of sedative therapy (SMST) in a sample of critically ill patients receiving mechanical ventilator support. The investigators hypothesis is that self-management of sedative therapy by mechanically ventilated patients in the intensive care unit (ICU), tailored to their individual needs will be more efficacious than nurse-administered sedative therapy in reducing anxiety, which may reduce duration of mechanical ventilator support and occurrence of delirium.
  • Pharmacogenomics and the Potential for Utilization of Testing Results for Patient Care in the Cardiac Surgical Intensive Care Unit Rochester, Minn.

    The overall goals of this pilot study are to: (1) describe pharmacogenomics (PGx) testing results and identify PGx variants that may inform treatment regimens and symptom management in cardiac surgical patients with an ICU stay, and (2) describe cardiac critical care team members’ awareness and attitudes towards the applications of pharmacogenomics testing results for their practice before and after completion of a PGx education module.
     
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