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Individualizing Corticosteroid Use in Pneumonia
Rochester, Minn.
The objectives of this study are to identify predictors of in-hospital disease progression (prognostic enrichment), to develop an individualized treatment rule (ITR) for steroid use through advanced statistical and machine learning methods (predictive enrichment), and to evaluate an ITR-guided corticosteroid use coupled with biomarker-guided dosing strategy (optimal patient selection and dosing) in community acquired pneumonia (CAP).
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