Faculty

Hu Zeng, Ph.D.

Clinical Studies

Biomarkers in Autoimmune and Inflammatory Diseases Rochester, Minn.
The purpose of this study is to identify biomarkers in people with autoimmune or inflammatory disease and in healthy people. We will use these biomarkers to develop tests that will help us better understand the same biomarkers in the blood of people who have autoimmune and inflammatory diseases.
Immune Checkpoint Inhibition and Humoral Immune Response in Systemic Autoimmunity (ICIRA) Rochester, Minn.
The primary aims of this study are to determine the immunopathology and molecular mechanisms of clinically-used PD-1 and PDL1 blockade mediated autoimmune diseases, and to investigate how dysregulation of PD-1 signaling contributes to IA-irAE and seronegative RA in human subjects.
Immune Checkpoint Inhibition Induced Inflammatory Arthritis Correlates with Imbalance Between T-cell Exhaustion and Senescence (ICIAE) Rochester, Minn.
The purpose of this study is to systematically examine the immunological features between IA-irAE, classic inflammatory arthritis, ICI-controls and HC.

Immunological consequences of COVID-19 vaccination in patients with Rheumatic Diseases Rochester, Minn.
This research trial will study the immune respone to COVID-19 vaccination in patients with rheumatic diseases.
Immunological Perturbation in Patients with Birt-Hogg-Dube Syndrome Rochester, Minn.
The purpose of this study is to determine whether FLCN mutations affect immune cell homeostasis and function.