Guru G. Kowlgi, M.B.B.S., M.S.

Closed for Enrollment

• Non-invasive measurement of blood glucose, blood pressure and extrapolation of QRS complex using a wrist wearable photoplethysmography sensor Rochester, Minn.

  A non-invasive wrist-based photoplethysmography (PPG) sensor may detect changes in blood glucose level and blood pressure. The PPG signal may also be used to extrapolate a waveform that may be used as a surrogate for the cardiac QRS complex.

  Aims, purpose, or objectives:

  1. Measure systolic and diastolic blood pressure detected by a wrist-based sensor and compare against standard of care noninvasive cuff blood pressure measurements and/or invasive arterial line measurements.
  2. Extrapolate a surrogate waveform for the cardiac QRS complex by training and validating against the reference electrocardiograph (ECG) waveform.
  3. Measure blood glucose levels detected by a wrist-based sensor and compare against fingerstick data obtained four times daily in hospitalized diabetic patients
  4. Measure blood glucose levels detected by a wrist-based sensor and compare against whole blood glucose identified in hospitalized patients undergoing anticipated blood glucose measurements