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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 91-100 of 150 for Ovarian

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  1. A Phase 1b Trial of ATRC-101 in Adults With Advanced Solid Malignancies

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  2. Study of E7386 in Participants With Selected Advanced Neoplasms

    Scottsdale/Phoenix, AZ, Jacksonville, FL, Rochester, MN

  3. Nab-Paclitaxel and Bevacizumab in Treating Patients With Unresectable Stage IV Melanoma or Gynecological Cancers

    Rochester, MN, Scottsdale/Phoenix, AZ, Jacksonville, FL

  4. A Study to Evaluate the Effectiveness and Safety of Rivaroxaban as Prophylaxis Treatment for Venous Thromboembolism (VTE) in Ambulatory Cancer Patients

    Rochester, MN

  5. Study of the Safety, Pharmacokinetics and Efficacy of EDO-S101, in Patients With Advanced Solid Tumors

  6. An Investigational Immuno-therapy Study to Assess the Safety, Tolerability and Effectiveness of Anti-LAG-3 With and Without Anti-PD-1 in the Treatment of Solid Tumors

    Rochester, MN

  7. hTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of Relapse

    Rochester, MN, Scottsdale/Phoenix, AZ

  8. A Phase Ib Study Of Cobimetinib Administered In Combination With Niraparib, With or Without Atezolizumab, To Patients With Advanced Platinum-Sensitive Ovarian Cancer

    Jacksonville, FL

  9. A Phase 1/2 Study of CYT-0851 in B-Cell Malignancies and Advanced Solid Tumors

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  10. A Study of Mogamulizumab Combined with Nivolumab in Patients who have Locally Advanced or Metastatic Solid Tumors

    Jacksonville, FL

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