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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 281-290 of 841 for cardiovascular

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  1. A Study to Evaluate the Effect of the Transient Receptor Potential Vanilloid 4 (TRPV4) Channel Blocker, GSK2798745, on Pulmonary Gas Transfer and Respiration in Patients With Congestive Heart Failure

    Rochester, MN

  2. A Phase 2 Trial of AMI MultiStem® Therapy in Subjects With Non-ST Elevation Acute Myocardial Infarction

    Scottsdale/Phoenix, AZ

  3. A Study of the Use of the Hansen Medical System in Patients with Paroxysmal Atrial Fibrillation

  4. A Study to Evaluate the Effect of Motion and Poor Circulation on Various Pulse Oximeter Performances During Heart Failure Stress Tests

    Rochester, MN

  5. A Phase 3 Clinical Trial of CCX168 (Avacopan) in Patients With ANCA-Associated Vasculitis

    Rochester, MN

  6. PRESERVE-Zenith® Branch Endovascular Graft-Iliac Bifurcation Clinical Study

    Rochester, MN

  7. Use of Repetitive Facilitative Exercise Program in Established Stroke

    Rochester, MN

  8. SYMPHONY: A Study of Macitentan in Pulmonary Arterial Hypertension to Validate the PAH-SYMPACT

    Scottsdale/Phoenix, AZ

  9. Cardiac Resynchronization and Iodine Meta-Iodobenzylguanidine (MIBG) Imaging

    Rochester, MN

  10. A Study of New Technology CT Scans for checking Left Ventricular Assist Devices

    Rochester, MN

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