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Healthy Volunteer

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A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

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During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 31-40 of 841 for cardiovascular

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  1. Acute Effects of Inorganic Nitrite on Cardiovascular Hemodynamics in Heart Failure With Preserved Ejection Fraction

    Rochester, MN

  2. Cardiovascular Effects of Adderall in Healthy Young Adults

    Rochester, MN

  3. A Study to Evaluate Cardiovascular Effects of High Intensity Interval Training in Individuals with Paraplegia

    Rochester, MN

  4. A Study of the Effect of Dalcetrapib on Cardiovascular Risk for a Genetically Defined Population who have had a Recent Acute Coronary Syndrome Event

  5. Pemafibrate to Reduce Cardiovascular OutcoMes by Reducing Triglycerides IN patiENts With diabeTes (PROMINENT)

  6. A Study to Compare the Rate of Major Cardiovascular Implantable Electronic Device Infections with the Absorbable Antibacterial Envelope and without

    Rochester, MN

  7. A Study of RoActemra/Actemra (Tocilizumab) in Comparison to Etanercept in Patients With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors

    Rochester, MN

  8. The Combined Influence of Pedal Rate and Venous Distension on Exercise Activation of Locomotor Afferents and Cardiovascular Responses

    Rochester, MN

  9. Using Ultrasonography, Shear Wave Elastography, Strain Imaging, and 3-D Volume Ultrasonography on Cardiovascular Disease

    Rochester, MN

  10. EdoxabaN or Warfarin Therapy In Cardiovascular Implantable Electrical Device Procedures in Patients With Non-Valvular Atrial Fibrillation

    Jacksonville, FL

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