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Healthy Volunteer

What is this?
A volunteer subject with no known significant health problems who participates in research to test a new drug, device or intervention. These volunteers are recruited to serve as controls for patient groups. Healthy volunteers receive the same test, procedure, or drug the patient group receives.

Study phase

What is this?
During the early phases (phases 1 and 2), researchers assess safety, side effects, optimal dosages and risks/benefits. In the later phase (phase 3), researchers study whether the treatment works better than the current standard therapy. They also compare the safety of the new treatment with that of current treatments. Phase 3 trials include large numbers of people to make sure that the result is valid. There are also less common very early (phase 0) and later (phase 4) phases. Phase 0 trials are small trials that help researchers decide if a new agent should be tested in a phase 1 trial. Phase 4 trials look at long-term safety and effectiveness, after a new treatment has been approved and is on the market.

Search Results 391-400 of 841 for cardiovascular

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  1. A Study Using Magnetic Resonance Elastography to Assess Heart Muscle Stiffness in Patients with Cardiac Amyloidosis

    Rochester, MN

  2. Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism

    Scottsdale/Phoenix, AZ, Rochester, MN, Jacksonville, FL

  3. Investigational Device Evaluation of the WATCHMAN FLX™ LAA Closure Technology

  4. Efficacy and Safety of Intranasal MSP-2017 for the Conversion of PSVT to Sinus Rhythm (NODE-1)

    Scottsdale/Phoenix, AZ

  5. A Study to Evaluate the Safety and Effectiveness of GORE® CARDIOFORM Septal Occluder to Treat Migraine Headaches

    Scottsdale/Phoenix, AZ

  6. Effects of Hyperglycemia on Myocardial Perfusion in Humans With and Without Type 2 Diabetes

    Rochester, MN

  7. An Extension Study to Evaluate Long-term Safety of Sacubitril/Valsartan in Pediatric Patients With Heart Failure (HF)

    Rochester, MN

  8. Study of Levosimendan in Pulmonary Hypertension Patients with Heart Failure and Preserved Left Ventricular Ejection Fraction (PHHFpEF)

    Rochester, MN

  9. The Ventilatory Response to Activation of the Locomotor Afferents in Normoxic and Hypoxic Conditions

    Rochester, MN

  10. A Multicenter Open Label Trial Using Ambrisentan in Patients with Porto-pulmonary Hypertension

    Jacksonville, FL

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